MISSENSE INTERPRETATION BY EXPERIMENTAL RESPONSE

The MITER classifier provides functional classification and supports quantitative predictions of pathogenicity for any missense variant using comprehensive experimental data. It currently supports functional classification for missense variants in the gene PPARG and quantitative predictions for familial partial lipodystrophy 3 (FPLD3) and Type 2 Diabetes.

Examples - Protein change: p.P12A or p.Pro12Ala, Genomic coordinates: chr3:12393125-C-G

Examples: 0.001 or 1.0e-5